Skip to main content
Skip to main content

Kinesiology, Recreation and Sport: Full-time Faculty - Jill Maples

Apply Now

Jill Maples, Ph.D., EP-C

Jill Maples, Ph.D., EP-C

Assistant Professor of Exercise Science

Office:  Smith Stadium East 1049
Phone:  (270) 745-4339
Email:  jill.maples@wku.edu

Courses

EXS 311 Exercise Physiology

EXS 310 Kinesiology

KIN 504 Advanced Exercise Physiology

 

 

 

 

Research

Research interest: Skeletal muscle metabolism in response to exercise, including the molecular mechanisms of how exercise improves the altered metabolism of individuals with metabolic disease including obesity and type 2 diabetes.

Selected publications:

Book Chapters

Maples JM, Houmard JA. Physical Activity for Obesity. In: Mullin G, Cheskin L, Matarese LE, editors. Integrative Weight Management. (submitted) 2013.

Peer-Reviewed Manuscripts

Maples JM, Brault JJ, Witczak CA, Park S, Hubal MJ, Weber TM, Houmard JA, Shewchuk BM. Differential epigenetic and transcriptional response of the skeletal muscle carnitine palmitoyltransferase 1B (CPT1B) gene to lipid exposure with obesity. American Journal of Endocrinology and Metabolism. 2015 Aug, 309(4):E345-E356.


Pierce JR, Maples JM, Hickner RC. IL-15 concentration in skeletal muscle and subcutaneous adipose tissue in lean and obese humans: local effect of IL-15 on adipose tissue lipolysis. American Journal of Physiology-Endocrinology and Metabolism. 2015 Jun, 308(12):E1131-E1139.


Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Carroll RG, Hubal MJ, Dubis G, Weber TM, Houmard JA. Skeletal muscle from the severely obese is metabolically inflexible in terms of gene regulation and DNA methylation in response to lipid oversupply. Physiological Genomics. 2015 May, 47(5):139-146.

 

Fisher-Wellman KH, Weber TM, Cathey BL, Brophy PM, Gilliam LA, Kane CL, Maples JM, Gavin TP, Cortright RN, Houmard JA, Neufer PD. Mitochondrial respiratory capacity and content are normal in young insulin-resistant obese humans. Diabetes. 2014 Jan, 63(1):132-41.

Gilliam LA, Fisher-Wellman KH, Lin C, Maples JM, Cathey BL, Neufer PD. The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle. Free Radical Biology and Medicine. 2013 Dec, 65:988-96.

Maples JM, Fitzhugh EC, Costello CA, Moustaid-Moussa N, Bassett DR, Spence ML, Greer BP. Physical activity, screen time, and prevalence of overweight/obesity among adolescents in a creative, problem-solving program. Food and Nutrition Sciences. 2012 Mar, 3:568-578.

Selected presentations:

Dickens BC*, Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Hubal MJ, Houmard JA. A High-Fat Diet Activates Inflammatory Signaling in Human Skeletal Muscle Cultures from Severely Obese Women. FASEB Journal. April 29:1 Sup. 2015.  (*Student in the Maples Lab)


Cox LM*, Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Hubal MJ, Houmard JA. Skeletal Muscle Peroxisome Proliferator-Activated Alpha is Differentially Regulated with Severe Obesity.  FASEB Journal.  April 29:1 Sup. 2015.  (*Student in the Maples Lab)

Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Carroll RG, Hubal MG, Dubis Weber TM, Houmard JA. Lipid Oversupply Remodels DNA Methylation and Histone Acetylation in the CPT1B Gene Promoter Region. Abstract accepted for oral presentation at the American College of Sports Medicine National Meeting in Orlando, FL, May 2014.

Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Carroll RG, Hubal MG, Dubis Weber TM, Houmard JA. Lipid exposure elicits differential responses in gene expression and DNA methylation in the skeletal muscle of severely obese individuals. Abstract accepted for poster presentation at the Kentucky Academy of Sciences Annual Meeting in Morehead, KY, November 2013.

Maples JM, Brault JJ, Shewchuk BM, Witczak CA, Carroll RG, Hubal MG, Dubis Weber TM, Houmard JA. Epigenetic modifications play a role in the differential transcriptional regulation of skeletal muscle CPT1B gene among lean and severely obese women in response to lipid. Abstract accepted for poster presentation at the Genomics in Metabolism Conference in Copenhagen, Denmark, November 2013.

Maples JM, Park S, Ridings JD, Hubal MG, Consit LA, Brault JJ, Houmard JA. Lipid oversupply remodels DNA methylation in genes that play vital roles in fatty acid oxidation. Abstract accepted for poster presentation at the ECU Research & Creative Achievement Week in Greenville, NC, April 2013.

Maples JM, Hubal, MJ, Brault JJ, Weber TM, Dubis G, Consitt LA, Houmard JA. Coordinated upregulation of mitochondrial genes in response to fatty acids is depressed with severe obesity. Abstract accepted for poster presentation at the Southeast Chapter of the American College of Sports Medicine Regional Meeting in Greenville, SC, February 2013.

Maples JM, Brault JJ, Weber TM, Battaglia GM, Alavi S, Dubis G, Consitt LA, Houmard JA. The upregulation of genes involved in fatty acid oxidation is depressed with severe obesity. Abstract accepted for poster presentation, APS Integrative Biology of Exercise Meeting in Westminster, CO, October 2012.

Reed MA, Maples JM, Weber TM, Pories WJ, Houmard JA, Dohm GL, Gavin TP. Effect of chronic hyperinsulinemia on insulin signaling and mitochondria in lean and obese human myocytes. Abstract accepted for poster presentation, American College of Sports Medicine Annual Meeting in San Francisco, CA, May 2012.

Gilliam LA, Fisher-Wellman KH, Lin CT, Maples JM, Neufer PD. Doxorubicin impairs skeletal muscle mitochondrial respiratory capacity in skeletal muscle. Abstract accepted for poster presentation, Experimental Biology Meeting in San Diego, CA, April 2012.

Maples JM, Weber TM, Reed MA, Gavin TP, Pories WJ, Dohm GL, Houmard JA. Complete fatty acid oxidation is depressed following chronic hyperinsulinemia and hyperlipidemia in human myotubes from severely obese women. Abstract accepted for poster presentation, ECU Research & Creative Achievement Week in Greenville, NC, March 2012.

Maples JM, Weber TM, Reed MA, Gavin TP, Pories WJ, Dohm GL, Houmard JA. Fatty acid oxidation is depressed following chronic hyperinsulinemia and hyperlipidemia in human myotubes from severely obese individuals. Abstract accepted for poster presentation, Southeast Chapter of the American College of Sports Medicine Regional Meeting in Jacksonville, FL, February 2012.

Maples JM, Fitzhugh EC, Costello CA, Bassett DR, Spence ML, Greer BP, Gibbs R, Muenchen R, Moustaid-Moussa N. The Interaction between physical activity with sedentary behaviors & risk of overweight/obesity among adolescents. Selected for an oral presentation, Southeast Chapter of the American College of Sports Medicine Regional Meeting in Greenville, SC, February 2010.

Biography

Education: 

Ph.D:  East Carolina University - Greenville, NC
M.A:  The University of Tennessee – Knoxville, TN
B.S:   The University of Tennessee – Knoxville, TN

Professional Certifications
 
Primary Group Fitness Instructor - American Council on Exercise (ACE)
CPR/AED - American Heart Association

Professional Memberships

American Heart Association
American Physiological Society
Southeast Chapter of the American College of Sports Medicine
American College of Sports Medicine
Kentucky Rural Health Association
Kentucky Academy of Science
American Council on Exercise
 

Note: documents in Portable Document Format (PDF) require Adobe Acrobat Reader 5.0 or higher to view,
download Adobe Acrobat Reader.

Note: documents in Excel format (XLS) require Microsoft Viewer,
download excel.

Note: documents in Word format (DOC) require Microsoft Viewer,
download word.

Note: documents in Powerpoint format (PPT) require Microsoft Viewer,
download powerpoint.

Note: documents in Quicktime Movie format [MOV] require Apple Quicktime,
download quicktime.

 
 Last Modified 9/25/14