Skip to main content
Western Kentucky University
EMERGENCY ALERT SYSTEM:

WKU WEATHER ALERT:

WKU offices in Bowling Green will open at 10 a.m. Friday. Classes Friday remain canceled and campuses in Glasgow, Owensboro and Elizabethtown/Ft. Knox remain closed Friday. Saturday classes in Bowling Green will proceed as scheduled. Here is a link to the University’s attendance policy during adverse weather conditions. Use caution and watch for slick spots on roads and walks. 

Residence Halls remain open until noon Saturday. Bemis & Barnes have space for those who need to stay longer. Visit WKU Housing & Residence Life for more information.

The high school regional basketball tournament games scheduled for Wednesday night were canceled. Games will be rescheduled for Friday/Saturday. Follow WKU News for the latest updates. #WKUAlert

Biology Faculty and Staff - Ajay Srivastava

Ajay Srivastava, Ph.D. University of Alberta

Ajay Srivastava, Ph.D. University of Alberta

Assistant Professor

Office:  TCCW 351
Phone:  270-745-6008
Email:  ajay.srivastava@wku.edu
Website:  http://people.wku.edu/ajay.srivastava/index.html/Welcome.html
CV:  http://wku.edu/biology/ajay_srivastava_cv_f2014.pdf

Courses

Biol 120: Biological Concepts: Cell Metabolism and Genetics

Biol 327: Genetics

Biol 440: Developmental Genetics

Biol 475: Techniques in Developmental Biology

Biol 675: Drosophila Genetics and Cancer

Biol 675: Selected topics in Development

Research

Research in my lab takes advantage of the sophisticated genetic tools available in the model organism Drosophila to better understand and dissect the underlying mechanisms of normal development and disease. We are particularly interested in understanding the contributions of Extracellular Matrix to normal development and tumorigenesis. Development of Drosophila wing is another area of my labs’ interest as this is an excellent model for organogenesis where various events that give rise to an adult structure can be studied.  Several projects spanning the domain of our interest are available for motivated students. I welcome enquiries!

Bio

Postdoctoral (Developmental Genetics and Molecular Oncology), 2009: Yale University, New Haven, CT

Ph.D. (Molecular Biology and Genetics), 2003: University of Alberta, Edmonton, Canada

Publications

Srivastava, Ajay and Qian Dong. Regulation of a serine protease homolog by the JNK pathway during thoracic development of Drosophila melanogaster. FEBS Open Bio, 2015 (In Press)

Gillian E. Jones and Ajay Srivastava. Understanding Lunasin’s Biology and Potential as a Cancer Therapeutic by utilizing Drosophila Genetics. Experimental Biology and Medicine 2014; 239: 519–528. DOI: 10.1177/1535370214522180.

Srivastava, A.  A Protocol for Genetic Induction and Visualization of Benign and Invasive Tumors in Cephalic Complexes of Drosophila melanogaster. J. Vis. Exp. (79), e50624, doi:10.3791/50624 (2013).

Ajay Srivastava, Jose Carlos Pastor-Pareja, Tatsushi Igaki, Raymond Pagliarini and Tian Xu. Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proceedings of the National Academy of Sciences, USA. 2007 Feb 20; 104(8):2721-6. Epub 2007 Feb 14.

 Garg A, Srivastava A, Davis MM, O'Keefe S, Chow L, Bell JB.  Antagonizing Scalloped with a Novel Vestigial Construct Reveals an Important role for Scalloped in Leg, Eye and Optic Lobe Development of Drosophila melanogaster. Genetics 2007 Feb;175(2):659-69. Epub 2006 Nov 16.

Srivastava A, Simmonds AJ, Garg A, Fossheim L,Campbell SD, Bell JB. Molecular and functional analysis of scalloped lethal alleles in Drosophila melanogaster. Genetics 2004, 166(4):1833-43.

MacKay JO, Soanes KH, Srivastava A, Simmonds AJ, Brook WJ, Bell JB. An in vivo analysis of the vestigial gene in Drosophila melanogaster confirms domains required for VG function. Genetics 2003, 163-4; 1365-73.

Srivastava A, Bell JB. Further developmental roles of the vestigial / scalloped transcription complex during wing development in Drosophila melanogaster. Mechanisms of Development 2003, 120(5); 587-96.

Srivastava A, Heise C, Garg A, Bell JB. The relationship between the dominant Additional vein mutant in Drosophila melanogaster and engrailed. Genome 2002, 45; 1077-1082.

Srivastava A, MacKay JO, Bell JB. A Vestigial:Scalloped TEA domain chimera rescues the wing phenotype of a scalloped mutation in Drosophila melanogaster. Genesis 2002, 33(1); 40-47.

Note: documents in Portable Document Format (PDF) require Adobe Acrobat Reader 5.0 or higher to view,
download Adobe Acrobat Reader.

Note: documents in Excel format (XLS) require Microsoft Viewer,
download excel.

Note: documents in Word format (DOC) require Microsoft Viewer,
download word.

Note: documents in Powerpoint format (PPT) require Microsoft Viewer,
download powerpoint.

Note: documents in Quicktime Movie format [MOV] require Apple Quicktime,
download quicktime.

 
 Last Modified 9/25/14