Stress experienced by men alters sperm and affects children
|Author: Mustafa Zahmak (from United Press International---UPI)|
Date: Tuesday, June 18th, 2013
Stress as a pre-adolescent or adult leaves a lasting impression on a dad's sperm that gives his kids a blunted reaction to stress, U.S. researchers say.
Study leader Tracy L. Bale of the Perelman School of Medicine and the School of Veterinary Medicine at the University of Pennsylvania in Philadelphia said the findings point to a never-before-seen link to stress-related diseases such as anxiety and depression passed from father to child.
The study involved male mice exposed to six weeks of chronic stress, before breeding, either throughout puberty or only in adulthood. Examples of stress include sudden move to another cage, predator odor such as fox urine, noise, or a foreign object in the cage.
Male mice are ideal for such an experiment because they do not participate in offspring rearing, meaning any external factors outside of germ-cell formation are essentially eliminated, Bale said.
The study, published in the Journal of Neuroscience, found offspring from paternal stress groups displayed significantly blunted levels of the stress hormone corticosterone -- in humans, it's cortisol -- in response to stress.
This stress pathway dysregulation -- when reactivity to stress is either heightened or reduced -- is a sign an organism doesn't have the ability to respond appropriately to a changing environment and as a result, their stress response becomes irregular, which can lead to stress-related disorders, Bale said.
"It didn't matter if dads were going through puberty or in adulthood when stressed before they mated," Bale said in a statement. "We've shown here for the first time that stress can produce long-term changes to sperm that reprogram the offspring hypothalamic-pituitary-adrenal axis, a region of the brain that governs responses to stress."
- All Categories
- CHHS October 2011 E-Newsletter
- CHHS November 2011 E-Newsletter
- CHHS December 2011 E-Newsletter
- CHHS January 2012 E-Newsletter
- CHHS February 2012 E-Newsletter
- CHHS March 2012 E-Newsletter
- CHHS April 2012 E-Newsletter
- CHHS May 2012 E-Newsletter
- CHHS June 2012 E-Newsletter
- CHHS July 2012 E-Newsletter
- CHHS August 2012 E-Newsletter
- CHHS September 2012 E-Newsletter
- CHHS October 2012 E-Newsletter
- CHHS November 2012 E-Newsletter
- CHHS December 2012 E-Newsletter
- CHHS January 2013 E-Newsletter
- CHHS February 2013 E-Newsletter
- CHHS March 2013 E-Newsletter
- CHHS April 2013 E-Newsletter
- CHHS May/June 2013 E-Newsletter
- CHHS July 2013 E-Newsletter
- Archived CHHS News
- CHHS October 2013 E-Newsletter
- CHHS November 2013 E-Newsletter
- CHHS September 2011 E-Newsletter
- CHHS August 2011 E-Newsletter
- CHHS July 2011 E-Newsletter
- CHHS June 2011 E-Newsletter
- CHHS May 2011 E-Newsletter
12/12 and 12/13
Saturday, December 14th
Journalism Scholars Day, a 41-year tradition at WKU, attracted more than 385 Kentucky high school journalism students from 15 schools across the state to campus on Nov. 15.
The Fall Super Saturdays program, which is put on by The Center for Gifted Studies, hosted more than 500 first through eighth graders from two states and more than 40 school districts each Saturday from Nov. 2 to Nov. 23.